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As a result, in vitro findings may not reliably predict the biological efficacy or safety of antioxidants in living systems (Warsinah et al., 2020

However, the complex machinery underlying CIPN is poorly understood

It serves as a building block for DNA and RNA production and also assists the nervous system in proper functioning

140 In addition to the side effects already mentioned, arginine supplementation is associated with a wide range of other unpleasant symptoms: heart palpitations, dizziness, light-headedness, irritability, depression, anxiety, dehydration, headache, restless legs, indigestion, swollen legs, chest pain, low blood sugar, lower back pain, blood abnormalities, breathing problems, worsened asthma, elevated homocysteine and worsened kidney disease and sickle cell disease